develops medicines MORE EFFECTIVE
American researchers decoded the complete genome structure of the AIDS virus, which that could accelerate research to develop new antiretroviral drugs, according to articles publicados por la revista científica británica “Nature”.
Este trabajo abre la vía a nuevas investigaciones que deberían favorecer una mejor comprensión de las estrategias de infección del virus, según sus autores.
Kevin Weeks (de la Universidad de Carolina del Norte) y sus colegas consiguieron una larga “vista aérea” de la arquitectura del genoma del virus y de sus funciones posibles. “Empezamos igualmente a comprender las estrategias del genoma que permiten al virus escapar de la detección de su anfitrión humano”, comenta Kevin Weeks.
Los investigadores muestran así que la formación de proteínas is influenced by elements of the internal structure of RNA. Suggesting that the RNA structure itself may play a role, hitherto unrecognized in the expression of the genetic code, the researchers said.
biologists specializing in the study of structures can now use this map of the genome big plans to make judgments on certain regions of the genome of HIV-1 and explore before their atom-level functions as the scientific journal Hashim Al-Hashimi. " It seems that the quest to have a finer view, high resolution, the structure of the entire genome has begun seriously, he writes. In fact, the genome of this virus has not yet revealed all its mysteries.
CHEAPER DRUGS
Meanwhile, the foundation of former President Bill Clinton signed agreements with two pharmaceutical companies in order to offer lower prices on medicines for patients in poor countries suffering from drug-resistant AIDS. One of the agreements, Mylan Laboratories, will reduce the annual price of four antiretroviral drugs used as second line treatment for patients with HIV who develop resistance to the first drugs with which they are served.
The other agreement, Pfizer will reduce the cost a drug that can be used with other drugs to treat patients infected with tuberculosis.
"This is a very important agreement," said former U.S. President Bill Clinton on Thursday on the announcement.
POINTS
HIV, such as influenza virus, hepatitis C and polio, is genetic information stored in a molecule of ribonucleic acid (RNA), whereas the mammalian genome is part of the double helix of DNA (deoxyribonucleic acid). However, the information contained in RNA is much more complex.
THE NUMBER
U.S. $ 425 year will cost the group of drugs-to be taken once a day, Mylan Labs.
Trade; Saturday August 8, 2009.
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